Kluṛukin

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Test tube icon.svgKluṛukin
Tanga takrurant Uddis akruran, asafar, médicament essentiel (fr) Suqel, quinoline alkaloid (en) Suqel d chemical entity class (en) Suqel
Takura tacubrant 319,182 Da
Trouvé dans le taxon (fr) Suqel Cinchona calisaya (fr) Suqel
Rôle (fr) Suqel DNA polymerase inhibitors (en) Suqel, antirhumatismaux modificateurs de la maladie (fr) Suqel, amœbicide (fr) Suqel d antipaludéen (fr) Suqel
Tamsuka takrurant
Taftart takrurant C₁₈H₂₆ClN₃
Chloroquine.svg
SMILES canonique (fr) Suqel
Model 2D
CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
InChI (fr) Suqel Model 3D
Propriété (fr) Suqel
PKa (fr) Suqel 10,18
10,2
Nniḍen
amertume (fr) Suqel

Kluṛukʷin (S Teglizit: Chloroquine) d asafar yettusmersen (yettusxedmen) i taggaẓt ɣef Malaṛya d ussuji-ynes deg yideggan id teṭṭurray.[1]. Deg kra n tikwal, kra n telmas n Malaṛya d tdefrin tinazbayin ssuturent isafaren niden yemgaraden. Akken i yettusemres deg kra n tikwal i wsuji n waṭṭan n ambyasis id yettilin deg beṛṛa n wadan d uzuwerzellim d tmuccent. Asafar-a yettwasew s yimi

isemda imezluga imezdiyen gan d uguren deg tmaẓwalin d tunɣayt d uberriṭ (tadist).[1]. Ma d isemda imezluga imihanen gan d uguren deg usekkud d uttwiɣi n tmaẓwalin d tezɣint n tegrint d wuzuf aplestin. Macc yettuɣil d akken asafar-a d aneɣlis deg tallit n tadist.[2] Akken daɣen id tella tezrawt i wakken ad ẓṛen ma yezmer ad yessuji aṭṭan n COVID-19 as of 2020.[3]

Asafar-a yettusnirem-d deg useggas n 1934 sɣur Hans Andersag.[4][5] deg wumuɣ n yisafaren igejdanen imudmawen n tuddsa tamadlant n tdawsa, akken igan d isafaren imazgayen deg unagraw adawsan yettumeggzen tamɣellist.[6]

Tirrayin n usemres[ẓreg | ẓreg aɣbalu]

Isemda imezluga[ẓreg | ẓreg aɣbalu]

Tigmayin[ẓreg | ẓreg aɣbalu]

Tamellilt[ẓreg | ẓreg aɣbalu]

  1. 1,0 et 1,1 Empty citation (help)
  2. Empty citation (help)
  3. Cortegiani A, Ingoglia G, Ippolito M, Giarratano A, Einav S. doi:10.1016/j.jcrc.2020.03.005. PMID 32173110. Unknown parameter |azmez= ignored (help); Unknown parameter |azwel= ignored (help); Unknown parameter |aɣmis= ignored (help); Cite journal requires |journal= (help); Missing or empty |title= (help)
  4. Manson's tropical diseases (22nd ed.). [Edinburgh]: Saunders. 2009. p. 1240. ISBN 9781416044703. Archived from the original on 2 November 2018. Retrieved 9 September 2017.
  5. Bhattacharjee M (2016). Chemistry of Antibiotics and Related Drugs. Springer. p. 184. ISBN 9783319407463. Archived from the original on 1 November 2018. Retrieved 9 September 2017.
  6. Talɣa:Taganit s wedlis